Lpcat2 (NM_173014) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR218203L4V
- LentiORF®
Lenti ORF particles, Lpcat2 (GFP-tagged) - Mouse lysophosphatidylcholine acyltransferase 2 (Lpcat2), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
Product Data | |
Product Name | Lpcat2 (NM_173014) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | A330042H22; Aytl1; Aytl1a; lpafat1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_173014 |
ORF Size | 1632 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR218203).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_173014.1 |
RefSeq Size | 2800 bp |
RefSeq ORF | 1635 bp |
Locus ID | 270084 |
Gene Summary | Possesses both acyltransferase and acetyltransferase activities (PubMed:17182612, PubMed:18156367). Activity is calcium-dependent (PubMed:17182612). Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (PubMed:17182612). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor (PubMed:17182612, PubMed:18156367). Under resting conditions, acyltransferase activity is preferred (PubMed:17182612). Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases (PubMed:17182612). Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine. Involved in the regulation of lipid droplet number and size (By similarity).[UniProtKB/Swiss-Prot Function] |
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