Cyr61 (NM_010516) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR221828L4V
- LentiORF®
Lenti ORF particles, Cyr61 (GFP-tagged) - Mouse cysteine rich protein 61 (Cyr61), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Cyr61 (NM_010516) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI325051; CCN1; Igfbp10 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_010516 |
ORF Size | 1137 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR221828).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010516.2, NP_034646.1 |
RefSeq Size | 2028 bp |
RefSeq ORF | 1140 bp |
Locus ID | 16007 |
Gene Summary | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CCN1-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity).[UniProtKB/Swiss-Prot Function] |
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