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Dmpk (NM_032418) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222017L4V
- LentiORF®
-
Lenti ORF particles, Dmpk (GFP-tagged) - Mouse dystrophia myotonica-protein kinase (Dmpk), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 12,255.00
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Specifications
| Product Data | |
| Product Name | Dmpk (NM_032418) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | DM; Dm15; DMK; MDPK; MT-PK |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_032418 |
| ORF Size | 1893 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222017).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_032418.2 |
| RefSeq Size | 2761 bp |
| RefSeq ORF | 1896 bp |
| Locus ID | 13400 |
| Gene Summary | The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appears to play a role in myogenesis. In adults, the transcript is localized to several tissues including brain, heart, and skeletal and smooth muscle, and a function in cytoskeletal remodeling has been described. Transcripts with expanded CUG repeats in the 3' untranslated region mediate alternative splicing of several genes and sequester RNA binding proteins and RNA transcripts that contain CAG repeats, resulting in myotonic dystrophy, an autosomal dominant neuromuscular disorder. Alternative splicing results in multiple protein coding and non-coding transcript variants. [provided by RefSeq, Oct 2014] |
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