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Ffar1 (NM_194057) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222997L3V
- LentiORF®
-
Lenti ORF particles, Ffar1 (Myc-DDK-tagged) - Mouse free fatty acid receptor 1 (Ffar1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Ffar1 (NM_194057) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Gpr40 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_194057 |
| ORF Size | 900 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222997).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_194057.2, NP_918946.2 |
| RefSeq Size | 903 bp |
| RefSeq ORF | 903 bp |
| Locus ID | 233081 |
| Gene Summary | G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (PubMed:23335512). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.[UniProtKB/Swiss-Prot Function] |
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