Trim14 (NM_029077) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR224121L4V

  • LentiORF®

Lenti ORF particles, Trim14 (GFP-tagged) - Mouse tripartite motif-containing 14 (Trim14), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,880.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Trim14 (NM_029077) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 5830400N10Rik; pub
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_029077
ORF Size 1320 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR224121).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_029077.4, NP_083353.1
RefSeq Size 3204 bp
RefSeq ORF 1323 bp
Locus ID 74735
Gene Summary Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways. Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593). Inhibits the transcriptional activity of SPI1 in a dose-dependent manner (PubMed:14592421).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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