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Nectin3 (NM_021495) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR224209L3V
- LentiORF®
-
Lenti ORF particles, Pvrl3 (Myc-DDK-tagged) - Mouse poliovirus receptor-related 3 (Pvrl3), transcript variant alpha, 200ul, >10^7 TU/mL
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CNY 10,070.00
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Specifications
| Product Data | |
| Product Name | Nectin3 (NM_021495) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2610301B19Rik; 3000002N23Rik; 4921513D19Rik; AA407785; AU016832; AW538082; CD113; Pvrl3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_021495 |
| ORF Size | 1647 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR224209).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021495.4, NP_067470.1 |
| RefSeq Size | 2169 bp |
| RefSeq ORF | 1650 bp |
| Locus ID | 58998 |
| Gene Summary | Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectins-like or other nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.[UniProtKB/Swiss-Prot Function] |
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