Cd22 (NM_001043317) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR225294L4V
- LentiORF®
Lenti ORF particles, Cd22 (GFP-tagged) - Mouse CD22 antigen (Cd22), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 15,200.00
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Specifications
Product Data | |
Product Name | Cd22 (NM_001043317) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | A530093D23; Lyb-8; Lyb8 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001043317 |
ORF Size | 2604 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225294).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001043317.2, NP_001036782.1 |
RefSeq Size | 4097 bp |
RefSeq ORF | 2607 bp |
Locus ID | 12483 |
Gene Summary | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.[UniProtKB/Swiss-Prot Function] |
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