Amh (NM_007445) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR225495L4V
- LentiORF®
Lenti ORF particles, Amh (GFP-tagged) - Mouse anti-Mullerian hormone (Amh), 200ul, >10^7 TU/mL
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CNY 11,305.00
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Specifications
Product Data | |
Product Name | Amh (NM_007445) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | M; MIS |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_007445 |
ORF Size | 1662 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225495).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_007445.2 |
RefSeq Size | 1665 bp |
RefSeq ORF | 1665 bp |
Locus ID | 11705 |
Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Homozygous knockout male mice develop female reproductive organs and are often sterile, while homozygous knockout female mice exhibit premature depletion of primordial follicles. [provided by RefSeq, Jul 2016] |
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