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Scd1 (NM_009127) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR225893L3V
- LentiORF®
-
Lenti ORF particles, Scd1 (Myc-DDK-tagged) - Mouse stearoyl-Coenzyme A desaturase 1 (Scd1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Scd1 (NM_009127) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA589638; ab; AI265570; Scd; Scd-1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009127 |
| ORF Size | 1065 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225893).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009127.4, NP_033153.2 |
| RefSeq Size | 4844 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 20249 |
| Gene Summary | Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the Delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:11500518, PubMed:11533264, PubMed:16275639, PubMed:16443825, PubMed:26098370). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:11500518, PubMed:11533264, PubMed:16443825, PubMed:26098370). Plays an important role in lipid biosynthesis (PubMed:17127673, PubMed:10899171, PubMed:11500518, PubMed:11441127, PubMed:11533264, PubMed:12177411, PubMed:26098370). Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (PubMed:12177411, PubMed:17127673, PubMed:24356954, PubMed:24295027). Plays an important role in body energy homeostasis (PubMed:17127673, PubMed:15210843, PubMed:24295027, PubMed:24356954). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (PubMed:10899171, PubMed:11500518, PubMed:11441127, PubMed:11533264, PubMed:12177411, PubMed:15210843, PubMed:26098370). Required for normal development of sebaceous glands (PubMed:17738154, PubMed:11533264). Required for the biosynthesis of normal levels of Delta-9 unsaturated fatty acids and 1-alkyl-2,3-diacylglycerol in the Harderian gland (PubMed:11500518). Required for normal production of meibum, an oily material that prevents drying of the cornea (PubMed:11533264).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
An N-terminal di-proline motif is essential for fatty acid–dependent degradation of Δ9-desaturase in Drosophila
,null,
The Journal of Biological Chemistry
,PubMed ID 28972163
[Scd1]
|
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