Ndst1 (NM_008306) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226583L4V
- LentiORF®
Lenti ORF particles, Ndst1 (GFP-tagged) - Mouse N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 (Ndst1), 200ul, >10^7 TU/mL
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CNY 15,390.00
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Specifications
Product Data | |
Product Name | Ndst1 (NM_008306) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1200015G06Rik; b2b2230Clo; Hsst; NDST-1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_008306 |
ORF Size | 2646 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226583).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008306.4 |
RefSeq Size | 6088 bp |
RefSeq ORF | 2649 bp |
Locus ID | 15531 |
Gene Summary | Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).[UniProtKB/Swiss-Prot Function] |
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