Cd19 (NM_009844) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226845L3V
- LentiORF®
Lenti ORF particles, Cd19 (Myc-DDK-tagged) - Mouse CD19 antigen (Cd19), 200ul, >10^7 TU/mL
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CNY 10,070.00
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Specifications
Product Data | |
Product Name | Cd19 (NM_009844) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AW495831 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_009844 |
ORF Size | 1641 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226845).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009844.2, NP_033974.2 |
RefSeq Size | 2440 bp |
RefSeq ORF | 1644 bp |
Locus ID | 12478 |
Gene Summary | Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores (PubMed:9382888, PubMed:12387743, PubMed:20101619). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:7542548, PubMed:7543183, PubMed:9317126). Required for normal differentiation of B-1 cells (PubMed:7542548, PubMed:7543183, PubMed:12387743). Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:7542548, PubMed:9317126, PubMed:12387743). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:7542548, PubMed:7543183, PubMed:12387743).[UniProtKB/Swiss-Prot Function] |
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