Gata4 (NM_008092) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227022L3V
- LentiORF®
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Lenti ORF particles, Gata4 (Myc-DDK-tagged) - Mouse GATA binding protein 4 (Gata4), 200ul, >10^7 TU/mL
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CNY 8,835.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Gata4 (NM_008092) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Gata-4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008092 |
ORF Size | 1326 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227022).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008092.3, NP_032118.2 |
RefSeq Size | 3393 bp |
RefSeq ORF | 1326 bp |
Locus ID | 14463 |
Gene Summary | Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (By similarity). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (PubMed:9584153). Promotes cardiac myocyte enlargement (By similarity). Required during testicular development (By similarity). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas
,null,
The Journal of Experimental Medicine
,PubMed ID 21464220
[Gata4]
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