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Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203809L4V
- LentiORF®
-
Lenti ORF particles, METAP2 (mGFP-tagged) - Human methionyl aminopeptidase 2 (METAP2), 200ul, >10^7 TU/mL
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CNY 9,975.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MAP2; MNPEP; p67eIF2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_006838 |
| ORF Size | 1434 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203809).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006838.3 |
| RefSeq Size | 3506 bp |
| RefSeq ORF | 1437 bp |
| Locus ID | 10988 |
| Domains | Peptidase_M24 |
| Protein Families | Druggable Genome, Protease |
| MW | 52.7 kDa |
| Gene Summary | The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
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