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EDG1 (S1PR1) (NM_001400) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204608L1V
- LentiORF®
-
Lenti ORF particles, S1PR1 (Myc-DDK tagged) - Human sphingosine-1-phosphate receptor 1 (S1PR1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | EDG1 (S1PR1) (NM_001400) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CD363; CHEDG1; D1S3362; ECGF1; EDG-1; EDG1; S1P1 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001400 |
| ORF Size | 1146 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204608).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001400.2 |
| RefSeq Size | 3050 bp |
| RefSeq ORF | 1149 bp |
| Locus ID | 1901 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| MW | 42.8 kDa |
| Gene Summary | The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness
,null,
Journal of Cell Science
,PubMed ID 25588843
[S1PR1]
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