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RGS18 (NM_130782) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204634L4V
- LentiORF®
-
Lenti ORF particles, RGS18 (mGFP-tagged) - Human regulator of G-protein signaling 18 (RGS18), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | RGS18 (NM_130782) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | RGS13 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_130782 |
| ORF Size | 705 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204634).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_130782.2 |
| RefSeq Size | 2158 bp |
| RefSeq ORF | 708 bp |
| Locus ID | 64407 |
| Domains | RGS |
| MW | 27.6 kDa |
| Gene Summary | This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
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