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RPL7A (NM_000972) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204917L2V
- LentiORF®
-
Lenti ORF particles, RPL7A (mGFP-tagged) - Human ribosomal protein L7a (RPL7A), 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
| Product Data | |
| Product Name | RPL7A (NM_000972) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | L7A; SURF3; TRUP |
| Vector | pLenti-C-mGFP |
| ACCN | NM_000972 |
| ORF Size | 798 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204917).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000972.2 |
| RefSeq Size | 890 bp |
| RefSeq ORF | 801 bp |
| Locus ID | 6130 |
| Domains | Ribosomal_L7Ae |
| Protein Families | Druggable Genome |
| Protein Pathways | Ribosome |
| MW | 30 kDa |
| Gene Summary | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
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