Myosin Light Chain 2 (MYL2) (NM_000432) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC205932L1V
- LentiORF®
Lenti ORF particles, MYL2 (Myc-DDK tagged) - Human myosin, light chain 2, regulatory, cardiac, slow (MYL2), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | Myosin Light Chain 2 (MYL2) (NM_000432) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CMH10; MLC-2s/v; MLC2 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_000432 |
ORF Size | 498 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC205932).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000432.1 |
RefSeq Size | 855 bp |
RefSeq ORF | 501 bp |
Locus ID | 4633 |
Domains | EFh |
Protein Pathways | Cardiac muscle contraction, Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Tight junction |
MW | 18.8 kDa |
Gene Summary | Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Identification of MYLK3 mutations in familial dilated cardiomyopathy
,null,
Scientific Reports
,PubMed ID 29235529
[MYL2]
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