IKAP (IKBKAP) (NM_003640) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207686L2V
- LentiORF®
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Lenti ORF particles, IKBKAP (mGFP-tagged) - Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
Product Data | |
Product Name | IKAP (IKBKAP) (NM_003640) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | DYS; FD; IKAP; IKBKAP; IKI3; TOT1 |
Vector | pLenti-C-mGFP |
ACCN | NM_003640 |
ORF Size | 3996 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207686).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003640.2 |
RefSeq Size | 5917 bp |
RefSeq ORF | 3999 bp |
Locus ID | 8518 |
Domains | IKI3 |
Protein Families | Druggable Genome |
MW | 150.1 kDa |
Gene Summary | The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
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