DNMT3A (NM_175629) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC208192L1V
- LentiORF®
Lenti ORF particles, DNMT3A (Myc-DDK tagged) - Human DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
货期*
详询
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | DNMT3A (NM_175629) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | DNMT3A2; HESJAS; M.HsaIIIA; TBRS |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_175629 |
ORF Size | 2736 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208192).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_175629.1 |
RefSeq Size | 4395 bp |
RefSeq ORF | 2739 bp |
Locus ID | 1788 |
Protein Families | Druggable Genome |
Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways |
MW | 101.9 kDa |
Gene Summary | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice
,null,
Epigenetics & Chromatin
,PubMed ID 27413395
[DNMT3A]
|
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 22308499
[DNMT3A]
|
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