Calpain 7 (CAPN7) (NM_014296) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC208200L3V
- LentiORF®
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Lenti ORF particles, CAPN7 (Myc-DDK tagged) - Human calpain 7 (CAPN7), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | Calpain 7 (CAPN7) (NM_014296) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CALPAIN7; PALBH |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_014296 |
ORF Size | 2439 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208200).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014296.2 |
RefSeq Size | 4385 bp |
RefSeq ORF | 2442 bp |
Locus ID | 23473 |
Domains | Calpain_III, MIT |
Protein Families | Druggable Genome, Protease |
MW | 92.7 kDa |
Gene Summary | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008] |
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