RNF144 (RNF144A) (NM_014746) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC208254L1V
- LentiORF®
-
Lenti ORF particles, RNF144A (Myc-DDK tagged) - Human ring finger protein 144A (RNF144A), 200ul, >10^7 TU/mL
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CNY 8,170.00
货期*
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规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | RNF144 (RNF144A) (NM_014746) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | hUIP4; RNF144; UBCE7IP4 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_014746 |
ORF Size | 876 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208254).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014746.2 |
RefSeq Size | 5755 bp |
RefSeq ORF | 879 bp |
Locus ID | 9781 |
Domains | IBR |
Protein Families | Druggable Genome, Transmembrane |
MW | 32.7 kDa |
Gene Summary | This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2
,null,
Cell Death and Differentiation
,PubMed ID 31406303
[RNF144A]
|
RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells
,null,
Oncotarget
,PubMed ID 29212245
[RNF144A]
|
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