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AMPK beta 2 (PRKAB2) (NM_005399) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208766L2V
- LentiORF®
-
Lenti ORF particles, PRKAB2 (mGFP-tagged) - Human protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2), 200ul, >10^7 TU/mL
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CNY 9,120.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | AMPK beta 2 (PRKAB2) (NM_005399) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP |
| ACCN | NM_005399 |
| ORF Size | 816 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208766).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_005399.3 |
| RefSeq Size | 5431 bp |
| RefSeq ORF | 819 bp |
| Locus ID | 5565 |
| Domains | AMPKBI |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
| MW | 30.1 kDa |
| Gene Summary | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
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