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CRTR1 (TFCP2L1) (NM_014553) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209241L1V
- LentiORF®
-
Lenti ORF particles, TFCP2L1 (Myc-DDK tagged) - Human transcription factor CP2-like 1 (TFCP2L1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | CRTR1 (TFCP2L1) (NM_014553) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CRTR1; LBP-9; LBP9 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_014553 |
| ORF Size | 1437 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209241).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014553.1 |
| RefSeq Size | 4909 bp |
| RefSeq ORF | 1440 bp |
| Locus ID | 29842 |
| Protein Families | Transcription Factors |
| MW | 54.4 kDa |
| Gene Summary | Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity). Required for normal duct development in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity). Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity). Modulates the placental expression of CYP11A1 (PubMed:10644752).[UniProtKB/Swiss-Prot Function] |
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