Azurocidin (AZU1) (NM_001700) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC210151L4V
- LentiORF®
Lenti ORF particles, AZU1 (mGFP-tagged) - Human azurocidin 1 (AZU1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Azurocidin (AZU1) (NM_001700) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | AZAMP; AZU; CAP37; HBP; hHBP; HUMAZUR; NAZC |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001700 |
ORF Size | 753 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC210151).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001700.3 |
RefSeq Size | 912 bp |
RefSeq ORF | 756 bp |
Locus ID | 566 |
Domains | Tryp_SPc |
Protein Families | Druggable Genome, Protease |
MW | 26.89 kDa |
Gene Summary | Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015] |
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