United States
Germany
Japan
United Kingdom
China
SOCS7 (NM_014598) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211558L4V
- LentiORF®
-
Lenti ORF particles, SOCS7 (mGFP-tagged) - Human suppressor of cytokine signaling 7 (SOCS7), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 11,685.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | SOCS7 (NM_014598) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | NAP4; NCKAP4 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_014598 |
| ORF Size | 1743 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211558).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014598.1, NP_055413.1 |
| RefSeq Size | 2162 bp |
| RefSeq ORF | 1938 bp |
| Locus ID | 30837 |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
| MW | 62.8 kDa |
| Gene Summary | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
