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Pyruvate Kinase (PKLR) (NM_181871) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC212337L1V
- LentiORF®
-
Lenti ORF particles, PKLR (Myc-DDK-tagged)-Human pyruvate kinase, liver and RBC (PKLR), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,070.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | Pyruvate Kinase (PKLR) (NM_181871) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PK1; PKL; PKRL; RPK |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_181871 |
| ORF Size | 1629 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC212337).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_181871.1 |
| RefSeq Size | 2433 bp |
| RefSeq ORF | 1632 bp |
| Locus ID | 5313 |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus |
| MW | 58.3 kDa |
| Gene Summary | The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
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