PAM (NM_000919) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC212581L3V
- LentiORF®
-
Lenti ORF particles, PAM (Myc-DDK-tagged)-Human peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 17,195.00
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规格
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Specifications
Product Data | |
Product Name | PAM (NM_000919) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | PAL; PHM |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_000919 |
ORF Size | 2922 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC212581).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000919.2 |
RefSeq Size | 3960 bp |
RefSeq ORF | 2925 bp |
Locus ID | 5066 |
Domains | Cu2_monoox_C, NHL |
Protein Families | Druggable Genome, Transmembrane |
MW | 108.4 kDa |
Gene Summary | This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
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