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OGG1 (NM_016819) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC213394L2V
- LentiORF®
-
Lenti ORF particles, OGG1 (mGFP-tagged) - Human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1b, 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
| Product Data | |
| Product Name | OGG1 (NM_016819) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HMMH; HOGG1; MUTM; OGH1 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_016819 |
| ORF Size | 972 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC213394).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016819.2, NP_058212.1 |
| RefSeq Size | 2801 bp |
| RefSeq ORF | 975 bp |
| Locus ID | 4968 |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
| MW | 36.3 kDa |
| Gene Summary | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] |
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