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CYP11B2 (NM_000498) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC215476L1V
- LentiORF®
-
Lenti ORF particles, CYP11B2 (Myc-DDK tagged) - Human cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 9,595.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | CYP11B2 (NM_000498) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ALDOS; CPN2; CYP11B; CYP11BL; CYPXIB2; P-450C18; P450aldo; P450C18 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_000498 |
| ORF Size | 1509 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215476).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000498.2 |
| RefSeq Size | 2936 bp |
| RefSeq ORF | 1512 bp |
| Locus ID | 1585 |
| Protein Families | Druggable Genome |
| Protein Pathways | C21-Steroid hormone metabolism, Metabolic pathways |
| MW | 57.56 kDa |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Structural Insights into Aldosterone Synthase Substrate Specificity and Targeted Inhibition
,null,
Molecular Endocrinology
,PubMed ID 23322723
[CYP11B2]
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