GLI3 (NM_000168) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216945L3V

  • LentiORF®

Lenti ORF particles, GLI3 (Myc-DDK-tagged)-Human GLI family zinc finger 3 (GLI3), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11,210.00


货期*
详询

规格
    • 200 ul

Cited in 1 publication.

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Specifications

Product Data
Product Name GLI3 (NM_000168) Human Tagged ORF Clone Lentiviral Particle
Synonyms ACLS; GCPS; GLI3-190; GLI3FL; PAP-A; PAPA; PAPA1; PAPB; PHS; PPDIV
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_000168
ORF Size 4740 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC216945).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000168.5
RefSeq Size 8228 bp
RefSeq ORF 4743 bp
Locus ID 2737
Domains zf-C2H2
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
MW 169.86 kDa
Gene Summary This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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