ch TOG (CKAP5) (NM_001008938) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218282L1V
- LentiORF®
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Lenti ORF particles, CKAP5 (Myc-DDK tagged) - Human cytoskeleton associated protein 5 (CKAP5), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 21,660.00
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Specifications
Product Data | |
Product Name | ch TOG (CKAP5) (NM_001008938) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | ch-TOG; CHTOG; MSPS; TOG; TOGp |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_001008938 |
ORF Size | 6096 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218282).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001008938.1 |
RefSeq Size | 6730 bp |
RefSeq ORF | 6099 bp |
Locus ID | 9793 |
Protein Families | Druggable Genome |
MW | 225.5 kDa |
Gene Summary | This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
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