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ACAT1 (ACACA) (NM_198834) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC218293L1V
- LentiORF®
-
Lenti ORF particles, ACACA (Myc-DDK tagged) - Human acetyl-CoA carboxylase alpha (ACACA), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 21,660.00
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| Product Data | |
| Product Name | ACAT1 (ACACA) (NM_198834) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ACAC; ACACAD; ACC; ACC1; ACCA |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_198834 |
| ORF Size | 7149 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218293).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_198834.1, NP_942131.1 |
| RefSeq Size | 10018 bp |
| RefSeq ORF | 7152 bp |
| Locus ID | 31 |
| Protein Families | Druggable Genome |
| Protein Pathways | Fatty acid biosynthesis, Insulin signaling pathway, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism |
| MW | 269.8 kDa |
| Gene Summary | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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