PFKFB2 (NM_001018053) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219676L1V
- LentiORF®
Lenti ORF particles, PFKFB2 (Myc-DDK-tagged)-Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 9,215.00
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Specifications
Product Data | |
Product Name | PFKFB2 (NM_001018053) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | PFK-2/FBPase-2 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_001018053 |
ORF Size | 1413 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219676).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001018053.1 |
RefSeq Size | 3529 bp |
RefSeq ORF | 1416 bp |
Locus ID | 5208 |
Protein Families | Druggable Genome |
Protein Pathways | Fructose and mannose metabolism |
MW | 54.2 kDa |
Gene Summary | The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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