SPFH2 (ERLIN2) (NM_007175) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221700L1V
- LentiORF®
Lenti ORF particles, ERLIN2 (Myc-DDK tagged) - Human ER lipid raft associated 2 (ERLIN2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,695.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | SPFH2 (ERLIN2) (NM_007175) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C8orf2; Erlin-2; NET32; SPFH2; SPG18 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_007175 |
ORF Size | 1017 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221700).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_007175.5 |
RefSeq Size | 4767 bp |
RefSeq ORF | 1020 bp |
Locus ID | 11160 |
Domains | Band_7 |
MW | 37.7 kDa |
Gene Summary | This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer
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eLife
,PubMed ID 28191869
[ERLIN2]
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