SPFH2 (ERLIN2) (NM_001003790) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221757L4V
- LentiORF®
Lenti ORF particles, ERLIN2 (mGFP-tagged) - Human ER lipid raft associated 2 (ERLIN2), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | SPFH2 (ERLIN2) (NM_001003790) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C8orf2; Erlin-2; NET32; SPFH2; SPG18 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001003790 |
ORF Size | 456 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221757).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001003790.1 |
RefSeq Size | 1744 bp |
RefSeq ORF | 459 bp |
Locus ID | 11160 |
MW | 16.6 kDa |
Gene Summary | This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] |
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