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HECTD1 (NM_015382) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221760L1V
- LentiORF®
-
Lenti ORF particles, HECTD1 (Myc-DDK tagged) - Human HECT domain containing 1 (HECTD1), 200ul, >10^7 TU/mL
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CNY 21,660.00
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Specifications
| Product Data | |
| Product Name | HECTD1 (NM_015382) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | EULIR |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_015382 |
| ORF Size | 7836 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221760).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_015382.1, NP_056197.1 |
| RefSeq Size | 8974 bp |
| RefSeq ORF | 7833 bp |
| Locus ID | 25831 |
| Protein Families | Druggable Genome |
| MW | 289.2 kDa |
| Gene Summary | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.[UniProtKB/Swiss-Prot Function] |
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