PDCD10 (NM_145859) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221815L1V
- LentiORF®
Lenti ORF particles, PDCD10 (Myc-DDK tagged) - Human programmed cell death 10 (PDCD10), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
详询
规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | PDCD10 (NM_145859) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CCM3; TFAR15 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_145859 |
ORF Size | 636 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221815).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145859.1, NP_665858.1 |
RefSeq Size | 1313 bp |
RefSeq ORF | 639 bp |
Locus ID | 11235 |
Protein Families | Druggable Genome |
MW | 24.7 kDa |
Gene Summary | This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Endothelial cell clonal expansion in the development of cerebral cavernous malformations
,null,
Nature Communications
,PubMed ID 31235698
[PDCD10]
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