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DMGDH (NM_013391) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC223089L3V
- LentiORF®
-
Lenti ORF particles, DMGDH (Myc-DDK-tagged)-Human dimethylglycine dehydrogenase (DMGDH), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 15,675.00
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Specifications
| Product Data | |
| Product Name | DMGDH (NM_013391) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DMGDHD; ME2GLYDH |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_013391 |
| ORF Size | 2598 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC223089).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_013391.2 |
| RefSeq Size | 3104 bp |
| RefSeq ORF | 2601 bp |
| Locus ID | 29958 |
| Domains | DAO, GCV_T |
| Protein Pathways | Glycine, serine and threonine metabolism, Metabolic pathways |
| MW | 96.81 kDa |
| Gene Summary | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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