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SIK3 (NM_025164) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC223406L3V
- LentiORF®
-
Lenti ORF particles, SIK3 (Myc-DDK tagged) - Human SIK family kinase 3 (SIK3), 200ul, >10^7 TU/mL
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CNY 21,090.00
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规格
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Specifications
| Product Data | |
| Product Name | SIK3 (NM_025164) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | L19; QSK; SEMDK; SIK-3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_025164 |
| ORF Size | 3789 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC223406).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_025164.3, NP_079440.2 |
| RefSeq Size | 6072 bp |
| RefSeq ORF | 3966 bp |
| Locus ID | 23387 |
| Protein Families | Druggable Genome, Protein Kinase |
| MW | 139.8 kDa |
| Gene Summary | Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis (PubMed:30232230). Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus (By similarity).[UniProtKB/Swiss-Prot Function] |
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