FANCD2 (NM_001018115) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223535L4V

  • LentiORF®

Lenti ORF particles, FANCD2 (mGFP-tagged)-Human Fanconi anemia, complementation group D2 (FANCD2), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 24,035.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name FANCD2 (NM_001018115) Human Tagged ORF Clone Lentiviral Particle
Synonyms FA-D2; FA4; FACD; FAD; FAD2; FANCD
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001018115
ORF Size 4353 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC223535).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001018115.1
RefSeq Size 5134 bp
RefSeq ORF 4356 bp
Locus ID 2177
Protein Families Druggable Genome
MW 163.9 kDa
Gene Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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