DR3 (TNFRSF25) (NM_148966) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC224211L3V
- LentiORF®
Lenti ORF particles, TNFRSF25 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 25 (TNFRSF25), transcript variant 3, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
Product Data | |
Product Name | DR3 (TNFRSF25) (NM_148966) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | APO-3; DDR3; DR3; GEF720; LARD; PLEKHG5; TNFRSF12; TR3; TRAMP; WSL-1; WSL-LR |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_148966 |
ORF Size | 1140 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC224211).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_148966.1, NP_683867.1 |
RefSeq Size | 1527 bp |
RefSeq ORF | 1143 bp |
Locus ID | 8718 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
MW | 38.7 kDa |
Gene Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
You may also need
Customer
Reviews
Loading...