XPD (ERCC2) (NM_001130867) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC225633L3V
- LentiORF®
Lenti ORF particles, ERCC2 (Myc-DDK tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Product Name | XPD (ERCC2) (NM_001130867) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | COFS2; EM9; TFIIH; TTD; TTD1; XPD |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001130867 |
ORF Size | 1215 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC225633).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001130867.1, NP_001124339.1 |
RefSeq ORF | 1218 bp |
Locus ID | 2068 |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Nucleotide excision repair |
MW | 46.1 kDa |
Gene Summary | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
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SDS |