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Ataxin 3 (ATXN3) (NM_001164780) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC228117L4V
- LentiORF®
-
Lenti ORF particles, ATXN3 (mGFP-tagged)-Human ataxin 3 (ATXN3), transcript variant u, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Ataxin 3 (ATXN3) (NM_001164780) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AT3; ATX3; JOS; MJD; MJD1; SCA3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001164780 |
| ORF Size | 546 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC228117).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001164780.1 |
| RefSeq ORF | 549 bp |
| Locus ID | 4287 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 20.5 kDa |
| Gene Summary | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016] |
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