ALDH4A1 (NM_001161504) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC228933L3V
- LentiORF®
Lenti ORF particles, ALDH4A1 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 4 family, member A1 (ALDH4A1), transcript variant 3, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Product Name | ALDH4A1 (NM_001161504) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | ALDH4; P5CD; P5CDh |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001161504 |
ORF Size | 1509 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC228933).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001161504.1, NP_001154976.1 |
RefSeq Size | 3259 bp |
RefSeq ORF | 1512 bp |
Locus ID | 8659 |
Protein Families | Druggable Genome |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways |
MW | 55.1 kDa |
Gene Summary | This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009] |
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