United States
Germany
Japan
United Kingdom
China
MARCH I (MARCH1) (NM_001166373) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC229839L1V
- LentiORF®
-
Lenti ORF particles, MARCH1 (Myc-DDK tagged) - Human membrane-associated ring finger 1 (MARCH1), transcript variant 1, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,170.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | MARCH I (MARCH1) (NM_001166373) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MARCH-I; MARCH1; RNF171 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001166373 |
| ORF Size | 867 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC229839).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001166373.1, NP_001159845.1 |
| RefSeq ORF | 870 bp |
| Locus ID | 55016 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 32.8 kDa |
| Gene Summary | MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
其它MARCH I产品
Customer
Reviews
Loading...
