Abcd1 (NM_001108821) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR201592L4V
- LentiORF®
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Lenti ORF particles, Abcd1 (GFP-tagged ORF) - Rat ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), 200ul, >10^7 TU/mL
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CNY 13,585.00
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Specifications
Product Data | |
Product Name | Abcd1 (NM_001108821) Rat Tagged ORF Clone Lentiviral Particle |
Synonyms | RGD1562128 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001108821 |
ORF Size | 2211 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR201592).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001108821.1, NP_001102291.1 |
RefSeq Size | 3411 bp |
RefSeq ORF | 2214 bp |
Locus ID | 363516 |
Gene Summary | Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (PubMed:12176987). Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation (PubMed:25043761). Involved in several processes; namely, controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance. Controls also the cellular response to oxidative stress by regulating mitochondrial function like, mitochondrial oxidative phosphorylation and depolarization. And finally controls the inflammatory response by positively regulating peroxisomal beta-oxidation of VLCFAs (By similarity).[UniProtKB/Swiss-Prot Function] |
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