Agtrap (NM_001007654) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR206078L3V
- LentiORF®
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Lenti ORF particles, Agtrap (Myc-DDK-tagged ORF) - Rat angiotensin II receptor-associated protein (Agtrap), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Agtrap (NM_001007654) Rat Tagged ORF Clone Lentiviral Particle |
Synonyms | MGC95145 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001007654 |
ORF Size | 480 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR206078).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001007654.1, NP_001007655.1 |
RefSeq Size | 2179 bp |
RefSeq ORF | 483 bp |
Locus ID | 298646 |
Gene Summary | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway. Attenuates type-1 angiotensin II receptor growth promoting effect and angiotensin II-induced phosphorylation of protein kinase AKT and of STAT3.[UniProtKB/Swiss-Prot Function] |
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