P2RY5 (LPAR6) (NM_005767) Human Mutant ORF Clone

Specifications

Product Data
Product Name	P2RY5 (LPAR6) (NM_005767) Human Mutant ORF Clone
Mutation Description	E189K
Affected Codon#	189
Affected NT#	565
Nucleotide Mutation	LPAR6 Mutant (E189K), Myc-DDK-tagged ORF clone of Homo sapiens lysophosphatidic acid receptor 6 (LPAR6), transcript variant 1 as transfection-ready DNA
Effect	Woolly hir
Synonyms	ARWH1; HYPT8; LAH3; LPA-6; P2RY5; P2Y5
Vector	pCMV6-Entry
Tag	Myc-DDK
ACCN	NM_005767
ORF Size	1032 bp
Sequence Data	ORF Nucleotide Sequence (showhide) >RC402795 representing NM_005767 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTAAGCGTTAACAGCTCCCACTGCTTCTATAATGACTCCTTTAAGTACACTTTGTATGGGTGCATGT TCAGCATGGTGTTTGTGCTTGGGTTAATATCCAATTGTGTTGCCATATACATTTTCATCTGCGTCCTCAA AGTCCGAAATGAAACTACAACTTACATGATTAACTTGGCAATGTCAGACTTGCTTTTTGTTTTTACTTTA CCCTTCAGGATTTTTTACTTCACAACACGGAATTGGCCATTTGGAGATTTACTTTGTAAGATTTCTGTGA TGCTGTTTTATACCAACATGTACGGAAGCATTCTGTTCTTAACCTGTATTAGTGTAGATCGATTTCTGGC AATTGTCTACCCATTTAAGTCAAAGACTCTAAGAACCAAAAGAAATGCAAAGATTGTTTGCACTGGCGTG TGGTTAACTGTGATCGGAGGAAGTGCACCCGCCGTTTTTGTTCAGTCTACCCACTCTCAGGGTAACAATG CCTCAGAAGCCTGCTTTGAAAATTTTCCAGAAGCCACATGGAAAACATATCTCTCAAGGATTGTAATTTT CATCAAAATAGTGGGATTTTTTATTCCTCTAATTTTAAATGTAACTTGTTCTAGTATGGTGCTAAAAACT TTAACCAAACCTGTTACATTAAGTAGAAGCAAAATAAACAAAACTAAGGTTTTAAAAATGATTTTTGTAC ATTTGATCATATTCTGTTTCTGTTTTGTTCCTTACAATATCAATCTTATTTTATATTCTCTTGTGAGAAC ACAAACATTTGTTAATTGCTCAGTAGTGGCAGCAGTAAGGACAATGTACCCAATCACTCTCTGTATTGCT GTTTCCAACTGTTGTTTTGACCCTATAGTTTACTACTTTACATCGGACACAATTCAGAATTCAATAAAAA TGAAAAACTGGTCTGTCAGGAGAAGTGACTTCAGATTCTCTGAAGTTCATGGTGCAGAGAATTTTATTCA GCATAACCTACAGACCTTAAAAAGTAAGATATTTGACAATGAATCTGCTGCC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGA TAAGGTTTAA Protein Sequence (showhide) >RC402795 representing NM_005767 Red=Cloning site Green=Tags(s) MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTL PFRIFYFTTRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGV WLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIKIVGFFIPLILNVTCSSMVLKT LTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIA VSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIFDNESAA SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NP_005758
RefSeq Size	1032 bp
RefSeq ORF	1035 bp
Locus ID	10161
Domains	7tm_1
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
MW	37.8 kDa
Gene Summary	The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]

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