Human PACAP receptor (ADCYAP1R1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADCYAP1R1
Locus ID	117
Kit Components	GA100079G1, PACAP receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100079G2, PACAP receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100079G3, PACAP receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001118, NM_001199635, NM_001199636, NM_001199637
Synonyms	PAC1; PAC1R; PACAPR; PACAPRI
Summary	This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]

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