Human alpha 1a Adrenergic Receptor (ADRA1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ADRA1A
Locus ID	148
Kit Components	GA100102G1, alpha 1a Adrenergic Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100102G2, alpha 1a Adrenergic Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100102G3, alpha 1a Adrenergic Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000680, NM_001322502, NM_001322503, NM_001322504, NM_033302, NM_033303, NM_033304, NR_136343
Synonyms	ADRA1C; ADRA1L1; ALPHA1AAR
Summary	Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]

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